Biotechnology is a broad discipline in which biological processes, organisms, cells or cellular components are exploited to develop new technologies. New tools and products developed by biotechnologists are used in research, industry and the clinic, especially the genetic manipulation of microorganisms for the production of antibiotics, hormones, etc. Philosophy, on the other hand, is the study of the fundamental nature of knowledge, reality, and existence. Like many domain-specific subfields of philosophy, such as philosophy of physics and philosophy of biology, philosophy of technology is a comparatively young field of investigation. Philosophy of technology denotes a considerable variety of philosophical endeavors that all in some way reflect on technology. I, therefore, argue that philosophy of biology and technology played a vital role in emergence of a recognizable field as biotechnology. The origin of philosophy of technology can be considered to be in the second half of the 19th century, its origin often being located with the publication of the Ernst Kapp’s book, Grundlinien einer Philosophie der Technik (Kapp, 1877). Philosophy of technology continues to be a field in the making and as such is characterized by the coexistence of a number of different approaches to doing philosophy. This highlights a problem for anyone aiming to give a concise overview of the field. Greek Antiquity Philosophers in the Greek antiquity already addressed questions related to the making of things. The terms “technique” and “technology” have their roots in the ancient Greek notion of “techne”, that is, the body of knowledge associated with a particular practice of making (cf. Parry, 2008). In classical Greek philosophy, reflection on the art of making involved both reflection on human action and metaphysical belief about what the world was like. Great philosophers like Plato and Aristotle plays a key role in Philosophy of technology and biology. Plato unfolded a cosmology in which natural world was understood as having been made by a divine Demiurge, a creator who made the various things in the world by giving form to formless matter in accordance with eternal ideas. According to Plato (Laws, Book X) what craftsmen do when making artifacts is to imitate nature’s craftsmanship – a view that was widely endorsed in ancient Greek philosophy and continued to play an important role in later stages of thinking about technology. On Plato’s view, then, natural objects and man-made objects come into being in similar ways, both being made by an agent according to pre-determined plans, which is the basis for principle of biotechnology.